BIST® (Beads array In Single Tip) is a multiplex detection tool developed for automated simultaneous multi-item measurements.
1mm diameter beads coated with a single immobilized antibody, antigen or DNA fragment are lined up inside the BIST® tip. Sample is automatically pipetted through the tip, binding target substances to the beads. After an enzymatic reaction, signals can be detected and measured simultaneously from up to 20 different bead-targets.
| Assay | Items | Sample |
|---|---|---|
| Body testing (Obesity factors) | β3AR、UCP1、AGT235、MTHFR | |
| Application to health guidance, talent analysis, etc. | ||
| Allergic reaction tests | Cedar, cypress, ragweed, HD (tick, cat, dog etc.) | |
| Cancer markers | AFP (hepatoma), PSA (prostatic cancer), p53 antibody | |
| Cancer-related tests | HLA Typing, sugar chain detection | |
| Cardiac disease marker | Myoglobin, troponin, PCT | |
| Clinical testing items | TSH, Free T3, Free T4, AFP, albumin | |
| Infant mass screening | TSH, 17-OHP, Free T4 | Dried blood spot |
| Autoimmune diseases | ||
| Pharmacogenomics（PGx） | IK28, SYP2C19, EGFR (Iressa target agent) | |
| Immunodeficiency disease | CD3 (T lymphocytes), CD19 (B lymphocytes), CD45 (leukocyte) | |
| Food allergens | Wheat, buckwheat, peanuts, eggs, milk, shrimp, crab | Food |
| Genetically modified food (GMO) protein | Herbicide resistant enzyme PAT, CP4-EPSPS | Food (corn, soy beans) |
| Genetically modified food (GMO) genes | Specific gene detection | Food (corn, soy beans) |
| Crop production location identification, variety identification | Tuna variety identification, cashmere identification | Meat, hair, etc. |
| Food poisoning | Salmonella (bacteria) | Stool, food |
| Staphylococcus aureus (bacteria, toxins: enterotoxins) | ||
| Vibrio parahaemolyticus (bacteria) | ||
| Bacillus cereus (bacteria, toxins) | ||
| E. coli (bacteria, toxins) | ||
| Legal communicable disease | Cholera, dysentery, typhoid | Stool, food |
| Diarrheal viruses | Norovirus, rotavirus, adenovirus | |
| Enterohaemorrhagic E. coli | O157, O26 | |
| Infectious disease | Mumps, EV virus | |
| Water examination | Legionella | Water |
